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EBOO Therapy in San Diego

- EBOO is one of the most advanced types of medical ozone therapy.
- It enhances oxygen delivery, immune balance, circulation, and overall cellular resilience.
- It includes blood filtration, potentially reducing circulating inflammation debris.
Short for Extracorporeal Blood Oxygenation and Ozonation, EBOO is one of the most comprehensive forms of medical ozone therapy available. Rather than targeting a single symptom or organ system, it works at the level of the blood – supporting oxygen delivery, immune balance, circulation, and cellular resilience throughout the entire body.
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Cutting‑Edge Ozone in One Powerful Session
A state‑of‑the‑art therapy that merges the most advanced and powerful integrated‑medicine approach into a single, highly effective treatment, and our San Diego clinic reviews speak for themselves.
What is EBOO Ozone Therapy?
EBOO ozone therapy is an intravenous medical treatment in which blood is continuously withdrawn from the body, passed through a specialized filtration system, exposed to precise amounts of medical-grade ozone and oxygen, and then returned to circulation. Unlike more traditional ozone therapies – such as major autohemotherapy (MAH) or IV ozone push – EBOO:
- Treats large volumes of blood over an extended session
- Provides continuous, controlled ozone exposure
- Incorporates blood filtration, which may reduce circulating inflammatory debris
In a single session, multiple liters of blood may be treated. This systemic approach is what distinguishes EBOO from other ozone delivery methods and contributes to its broad-ranging effects.

Extracorporeal Blood Oxygenation and Ozonation (EBOO)
An advanced therapeutic treatment designed to enhance blood circulation, promote cellular healing, and optimize oxygen utilization at the cellular

How EBOO Ozone Therapy Works in the Body
Ozone therapy operates through controlled oxidative signaling, where the interaction of ozone with blood components fosters beneficial biochemical responses without causing harm.
Key effects of EBOO ozone therapy include enhanced oxygen delivery and circulation by improving red blood cell flexibility, aiding those with chronic fatigue, exercise intolerance, brain fog, or poor circulation. It regulates immune system signaling, balancing cytokine activity, thus benefiting individuals with chronic inflammation, immune dysregulation, or persistent infections. Additionally, ozone activates antioxidant defense pathways, boosting cellular support and improving energy levels, mental clarity, and resilience.
Finally, EBOO systems help reduce inflammatory and oxidative burdens by filtering the blood, promoting cleaner circulation and better vascular health.
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What to Expect During an EBOO Ozone Therapy Session
An EBOO session typically lasts 60 to 90 minutes and is performed in a medical setting using FDA-cleared equipment.
During treatment:
- Two IV lines are placed for continuous blood flow
- Blood is circulated through the EBOO system, ozonated, filtered, and returned
- Patients typically relax, read, or rest during the session
After treatment, some patients report:
- Increased energy or mental clarity
- A sense of improved circulation or warmth
- Mild fatigue as the body adjusts
Effects may be noticed after a single session, though benefits often build over time.
Who May Benefit from EBOO Ozone Therapy?
At Oasis Health and Medicine, EBOO ozone therapy is used selectively and thoughtfully, based on a patient’s health history and clinical presentation.
- Chronic fatigue or post-viral syndromes
- Autoimmune or inflammatory conditions
- Persistent or recurrent infections
- Mold or environmental toxin exposure
- Cardiovascular or circulatory concerns
- Neurological symptoms such as brain fog or cognitive fatigue
Thorough screening is essential. Conditions such as severe anemia, certain bleeding disorders, or unstable cardiovascular disease may require caution or exclusion.

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How EBOO Ozone Therapy Works at a Cellular Level
EBOO ozone therapy works through controlled oxidative signaling, not by acting as a drug or remaining as ozone in the body. When medical-grade ozone comes into contact with blood during EBOO, it reacts immediately with lipids and antioxidants in plasma. This reaction forms short-lived messenger molecules, primarily small amounts of hydrogen peroxide and lipid oxidation products. Ozone itself does not circulate in the body. These messengers trigger a series of adaptive cellular responses:
Boosts Antioxidants and Oxygen Delivery
- Activation of antioxidant defense pathways: The signaling molecules activate Nrf2, a key transcription factor that increases the production of endogenous antioxidants such as glutathione, catalase, and superoxide dismutase. This improves the cell’s ability to manage oxidative stress.
- Improved mitochondrial efficiency: By optimizing redox balance, ozone signaling enhances mitochondrial function and ATP production, supporting cellular energy and resilience.
- Enhanced oxygen delivery: Ozone improves red blood cell flexibility and oxygen release to tissues, supporting microcirculation without increasing blood oxygen saturation.
Enhances Immune Function and Reduces Inflammation
- Immune regulation: White blood cells receive signals that improve pathogen recognition and immune efficiency while helping moderate excessive inflammatory signaling.
- Reduced inflammatory burden: Continuous blood filtration during EBOO helps remove inflammatory debris, while ozone signaling downregulates pro-inflammatory mediators.

How EBO2 Differs from Standard Ozone Therapy
Traditional ozone therapy typically includes methods like rectal administration, topical application, or use in sauna cabins.
In contrast, EBOO therapy advances this technique by integrating ozone infusion with extracorporeal blood circulation. This more intricate procedure is usually performed in clinical settings under the guidance of qualified medical professionals, such as our team at Oasis Health and Medicine in San Diego, CA.
By extracting blood from the body and meticulously regulating ozone exposure, EBO2 provides a more thorough and potentially more effective approach to blood purification and oxygenation.
Evidence-Based Benefits of EBOO Ozone Therapy
While EBOO itself is a newer delivery method, the biological effects of medical ozone therapy are supported by decades of peer-reviewed research.
- Reduced Inflammation: Ozone has demonstrated the ability to modulate inflammatory mediators while increasing antioxidant capacity, contributing to improved inflammatory balance.
- Antimicrobial Activity: Medical ozone has well-documented antibacterial, antiviral, and antifungal properties. Importantly, it does not contribute to antimicrobial resistance. This has made ozone therapy an area of interest for supporting immune defenses in chronic or recurrent infections.
- Improved Blood Flow and Vascular Health: Research suggests ozone therapy improves blood rheology, red blood cell deformability, and endothelial function - factors that support healthy circulation and oxygen delivery.
- Support for Detoxification Processes: By improving oxygen availability and antioxidant activity, ozone therapy indirectly supports the body’s natural detoxification pathways, including liver and lymphatic function.
If you have underlying health conditions, are pregnant, or are taking medications, consult a doctor before starting EBOO therapy.
Why EBOO Ozone Therapy Stands Out Among Advanced Medical Therapies
EBOO ozone therapy represents a highly advanced approach to systemic support, working through improved oxygenation, immune regulation, mitochondrial efficiency, and circulatory health.
Rather than masking symptoms, EBOO supports foundational physiological processes that influence healing, resilience, and recovery. For appropriately selected patients, it can be a valuable option within an integrative medical care plan. At Oasis Health and Medicine, EBOO ozone therapy is offered with a strong emphasis on safety, precision, and individualized care.
Effects may be noticed after a single session, though benefits often build over time.
Ready to Learn if EBOO Ozone Therapy is Right for You?
If you’re interested in exploring whether EBOO ozone therapy is appropriate for your health goals, we invite you to take the next step. Book a discovery call with Oasis Health and Medicine to discuss your history and determine whether this advanced therapy is a good fit.
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FAQ
Is EBOO ozone therapy the same as IV ozone?
No. EBOO treats a significantly larger volume of blood and includes filtration, making it more comprehensive than standard IV ozone therapies.
How many EBOO sessions are needed?
The number of sessions varies depending on individual health concerns. Some patients notice benefits after one session, while others benefit from a series.
Is EBOO ozone therapy painful?
Most patients experience minimal discomfort, similar to standard IV therapy.
Can EBOO help with post-viral fatigue or long COVID?
Clinical experience suggests benefits related to immune regulation, circulation, and cellular energy support.



